HLH Symptoms

Typical symptoms of HLH besides;

1. persistent fever are pallor (paleness),

2. jaundice

3. liver and spleen enlargement,

4. neurological symptoms, such as irritability or even seizures.

The involvement of the bone marrow, the site of blood cell production, can lead to severe decline of the blood cell counts (red and white blood cells and platelets).  On bone marrow examination, histiocytes that are “eating” other blood cells (also known as phagocytosis) can be detected. Although the disease was named after this phenomenon, it can be absent at the onset or even throughout the course of the disease.

From (http://www.histio.org/site/c.kiKTL4PQLvF/b.1849851/k.E7DE/Symptoms.htm)

My daugther case she had

1. fever

2. liver and spleen enlarge

3. blood count is really decline. Normally when my daughter had infection she will get the fever following by the decrease of blood count.

4. recurrent infection
5. she will always refer to ward in hospital when got infection. Duration warded at least 1 week.